EDUCATION

Kauffman Teaching Certificate Program
Massachusetts Institute of Technology Teaching and Learning Lab
Spring 2015

An Introduction to Evidence-Based Undergraduate STEM Teaching
Vanderbilt University MOOC
Statement of Accomplishment with Distinction
Fall 2014

University of Wisconsin-Madison, Madison, WI
Doctorate, Cellular and Molecular Biology, 2004-2012

Rice University, Houston, TX
Bachelor of Arts, cum laude, Biochemistry / Computer Science, 2000-2004
GPA (Major / Overall): 3.87 / 3.76

PROFESSIONAL EXPERIENCE

MIT iGEM Team Lead Instructor, 2013-present

Advised teams of 12 undergraduates each summer in choosing, developing, executing and presenting an original research project in synthetic biology.  Developed pedegogical strategies for teaching undergraduate researchers necessary research skills, including reading scientific literature, experimental design, cloning and DNA manipulation, data analysis, and science communication.

Research Scientist in the laboratory of Professor Ron Weiss, 2012-present
MIT Synthetic Biology Center, Cambridge MA

Implemented synthetic gene networks in Saccharomyces cerevisiae and Chinese Hamster Ovary cells for intercellular signaling, quorum sensing, fate determination and two-dimensional patterning.  Wrote software for flow cytometry data analysis.  Secondary roles in scientific communication and analytical instrumentation.

 

Research Assistant with Dr. David C. Schwartz, 2004-2012
University of Wisconsin – Madison, Madison, WI

Used Optical Mapping, a novel genomics platform, to discover and characterize structural polymorphisms in the human genome. Used statistical, computational and experimental techniques to refine Optical Mapping protocols. Developed a Hidden Markov Model (HMM) for Optical Mapping data analysis.

Research Assistant with Dr. Janet Braam, 2003-2004
Rice University, Houston, TX

Created and screened transgenic Arabidopsis thaliana to investigate the transcription profile of calmodulin genes. Screened T-DNA insertion mutants in the calmodulin genes, and tested them under various environmental stresses.

Research Assistant with Dr. Michael W. Deem, 2002-2003
Rice University, Houston, TX

Implemented and tested a new energy model for a Monte Carlo molecular biophysics simulator.

Summer Medicine and Research Training Program, 2002
Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX

Implemented a “stitching” algorithm to order and orient sequence contigs in the finishing stages of the Human Genome Project.

PRESENTATIONS

Quantitative Flow Cytometry. Teague, B. MIT Synthetic Biology Center Technical Seminar Series. April – June 2017.

Intercellular Signalling in Yeast: Quorum Sensing and Spatial Patterning.  Teague, B et al.  Keystone Symposium on Precision Genome Engineering and Synthetic Biology, January 2015.

How to make a scientist.  Whitehead Seminar Series for High School Teachers.  December 2014.

Structural Polymorphism Discovery Using Optical Mapping – Intelligent Systems for Molecular Biology, July 2008

Validation of mammalian genome sequence using optical maps. Goldstein, S., Cook, A., Teague, B., et al. The Biology of Genomes. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 2005.

PUBLICATIONS

Teague B, Guye P, Weiss R. Synthetic Morphogenesis. Cold Spring Harbor Perspectives in Biology, DOI:10.1101/cshperspect.a023929.

Beal, J. et al. Reproducibility of Fluorescent Expression  from Engineered Biological Constructions in E. coli. PLOS ONE 11:e0150182 (2016)

Teague, B and Weiss, R. Synthetic communities, the sum of parts. SCIENCE 349:6251. 2015.

Zhou, S. et al. Optical Mapping and Nanocoding Systems Potentiate Genome Assembly and Discover Structural Variants. International Plant and Animal Genome Conference XXII 2014.

Teague, B. et al. High-resolution human genome structure by single molecule analysis. Proc Natl Acad Sci USA 107:10848. 2010.

Antonacci, F. et al. A large and complex structural polymorphism at 16p12.1 underlies microdeletion disease risk. Nature Genetics 42:745. 2010.

Church, DM. et al. Lineage-Specific Biology Revealed by a Finished Genome Assembly of the Mouse. PLoS Biology 7:e1000112. 2009.

Kidd, JM. et al. Mapping and sequencing of structural variation from eight human genomes. Nature 453:56. 2008.

Scherer, SE. et al. The finished DNA sequence of human chromosome 12. Nature440:346. 2006.

Ross, MT. et al. The DNA sequence of the human X chromosome. Nature 434:325. 2005.

HONORS

Computation in Biology and Medicine Traineeship, Awardee, 2007
Molecular Biosciences Training Grant, Awardee, 2004
Genomic Sciences Training Program, Offer, 2004
James B. Walker Award for Outstanding Senior in Biology, 2004
Rice Undergraduate Research Symposium, Winner, 2004
President’s Honor Roll, 2002-2004